location_onLondon, UK
watch_later Posted: Aug 21, 2024
Skills Required
Nice To Have skills
Job Description
We are looking for a skilled, hands-on chemistry lab technician to join our multi-disciplinary team in our mission to harness the potential of unculturable microbes.
Role
As a compound discovery technician, you will work across our Screening and Analytical Chemistry teams to support our vision to discover solutions to global issues, including the discovery of new antibiotics against drug-resistant bacteria and fungicides to address global food security. This interdisciplinary role would involve working closely with natural product chemists, data scientists, microbiologists and synthetic biologists. We welcome candidates who are keen to apply their chemistry background to solving real-world biological problems.
Teams
- Our Screening team conducts the bioassay screening of our microbial libraries against pathogens that have impact across healthcare and agriculture. They work closely with our Analytical Chemistry team to facilitate the bioactivity-driven identification, purification and structural characterisation of novel antimicrobial compounds. As compound discovery technician you will work across both teams to support the compound identification and purification pipelines.
- At Bactobio we use state-of-the-art data collection methods and a range of innovative bioinformatic approaches to unlock the potential of previously unexplored microbes. So far, we have cultured more than 3,000 diverse species and we continue to grow our unique library and increase our microbial capture rates using metagenomics and machine learning. We apply liquid-handling robotics and design of experiment methods to efficiently explore this novel genetic and chemical space and exploit it for antimicrobial discovery.
- The compound discovery platform is supported by a dedicated analytical chemistry suite, encompassing flash-column chromatography, analytical and preparative HPLC systems, QToF LCMS and access to 800 MHz NMR spectroscopy facilities.
Your responsibilities will include:
- Supporting the Screening and Analytical Chemistry teams in the extraction of microbial samples
- Supporting compound separation by HPLC
- LCMS sample preparation and data collection
- Meticulous data recording, sample tracking and upload
- Maintenance and upkeep of the analytical chemistry laboratory and equipment
- Ownership of project(s) and upskilling in various areas of the Bactobio pipeline
You should have:
- A Master’s degree or above in chemistry, or a BSc in chemistry plus equivalent experience
- Experience preparing extracts from biological samples
- Experience with chromatography methods, including HPLC and LCMS
- Interest in biotechnology and enthusiasm for scientific discovery
- Ability to work independently as well as within a team
Disclaimer: The jobs on Lifelancer Platform are posted by employers, recruiters and Lifelancer. We aim to provide value to Talent users by connecting them with a maximum number of curated job opportunities. However, Lifelancer doesn't represent job-offering companies and is not responsible for job advert content or updates. We aim to connect you with the employer, job source, or application link to the best of our ability. You can apply for this job on the company website.